immune system

noun

: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, special deposits of lymphoid tissue (as in the gastrointestinal tract and bone marrow), macrophages, lymphocytes including the B cells and T cells, and antibodies

Examples of immune system in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
That protein then trains the immune system to learn to attack cancer cells. Kiki Intarasuwan, CBS News, 20 Aug. 2026 Immunotherapy is a medication that helps the patient’s own immune system fight the cancer. Maggie Donahue, HEALTH, 20 Aug. 2026 It’s made with green tea to provide energy while suppressing your appetite, and goji berry to help your immune system. Bestreviews, Chicago Tribune, 20 Aug. 2026 While most healthy individuals recover within a week, some infections may result in a serious complication known as hemolytic uremic syndrome (HUS), particularly in young children, older adults, and individuals with weakened immune systems. Michele Laufik, Martha Stewart, 20 Aug. 2026 See All Example Sentences for immune system

Word History

First Known Use

1899, in the meaning defined above

Time Traveler
The first known use of immune system was in 1899

Browse Nearby Words

Cite this Entry

“Immune system.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/immune%20system. Accessed 23 Aug. 2026.

Kids Definition

immune system

noun
: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, lymphocytes, and antibodies

Medical Definition

immune system

noun
: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, special deposits of lymphoid tissue (as in the gastrointestinal tract and bone marrow), lymphocytes including the B cells and T cells, and antibodies

More from Merriam-Webster on immune system

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

More from Merriam-Webster