immune system

noun

: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, special deposits of lymphoid tissue (as in the gastrointestinal tract and bone marrow), macrophages, lymphocytes including the B cells and T cells, and antibodies

Examples of immune system in a Sentence

Recent Examples on the Web
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While most recover, some — particularly young babies, pregnant people and those with weak immune systems — are at higher risk of developing dangerous complications such as pneumonia, brain swelling, blindness or even death. Devi Shastri, Los Angeles Times, 20 June 2026 While most recover, some — including young babies, pregnant people and those with weak immune systems — are at higher risk of developing dangerous complications like pneumonia, brain swelling, blindness or even dying. Devi Shastri, Fortune, 20 June 2026 This herb may boost the immune system’s response to certain infections, including upper respiratory infections and skin infections. Carrie Madormo, Verywell Health, 20 June 2026 When the sugar enters the bloodstream through a lone star tick bite, the body's immune system can begin treating it as a threat. CBS News, 19 June 2026 See All Example Sentences for immune system

Word History

First Known Use

1899, in the meaning defined above

Time Traveler
The first known use of immune system was in 1899

Browse Nearby Words

Cite this Entry

“Immune system.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/immune%20system. Accessed 23 Jun. 2026.

Kids Definition

immune system

noun
: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, lymphocytes, and antibodies

Medical Definition

immune system

noun
: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, special deposits of lymphoid tissue (as in the gastrointestinal tract and bone marrow), lymphocytes including the B cells and T cells, and antibodies

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