immune system

noun

: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, special deposits of lymphoid tissue (as in the gastrointestinal tract and bone marrow), macrophages, lymphocytes including the B cells and T cells, and antibodies

Examples of immune system in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
In laboratory and animal models, researchers at Dartmouth Health in New Hampshire found that the telmisartan causes more damage to cancer cells’ DNA, thus helping the immune system recognize and attack certain types of tumors. Melissa Rudy, FOXNews.com, 31 Mar. 2026 For example, some promote growth hormones, while others modulate the immune system. Will Stone, NPR, 31 Mar. 2026 The new vaccine takes a similar approach to Lymerix, delivering a surface protein found on Lyme bacteria so the body’s immune system generates antibodies against it. Meg Tirrell, CNN Money, 31 Mar. 2026 Coccidioides can cause severe pulmonary disease and chronic infections in some cases, while Aspergillus species, especially drug-resistant strains, can lead to life-threatening infections in people with weakened immune systems. Brandi D. Addison, USA Today, 30 Mar. 2026 See All Example Sentences for immune system

Word History

First Known Use

1899, in the meaning defined above

Time Traveler
The first known use of immune system was in 1899

Browse Nearby Words

Cite this Entry

“Immune system.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/immune%20system. Accessed 2 Apr. 2026.

Kids Definition

immune system

noun
: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, lymphocytes, and antibodies

Medical Definition

immune system

noun
: the bodily system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymph nodes, special deposits of lymphoid tissue (as in the gastrointestinal tract and bone marrow), lymphocytes including the B cells and T cells, and antibodies

More from Merriam-Webster on immune system

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

More from Merriam-Webster